B12 plus three metabolic compounds. One injection. Energy, fat mobilization, and liver support in a single protocol.
B12 + MIC injection delivers methylcobalamin (B12), methionine, inositol, and choline directly into your system — bypassing first-pass liver metabolism and supporting the metabolic pathways most directly involved in energy production, fat transport, liver health, and cellular function.
Injectable delivery ensures your system receives the B vitamin and amino acids it needs for optimal energy metabolism and the cofactors required for your liver to process and export stored fat, support insulin signaling, and maintain hepatic function. This bundle combines B12’s energy and neurological benefits with the lipotropic support of MIC.
At Obsidian Genetics, we offer physician-supervised B12 + MIC bundles with personalized dosing schedules and protocols designed to work synergistically with other metabolic therapies like GLP-1 drugs.
B12 + MIC Injection
The B12 + MIC Bundle: Four Compounds
Each ingredient targets specific metabolic pathways. Together, they create a synergistic effect on energy production, fat mobilization, and liver health.
Supports ATP production and energy metabolism at the mitochondrial level. Essential for red blood cell production, nerve function, and methylation support. Bypasses digestive absorption for immediate bioavailability. Injectable B12 is especially important for those with absorption issues or elevated methylation demands.
Supports lipid transport and hepatic fat export. Acts as a precursor to glutathione, the body's master antioxidant. Prevents hepatic steatosis by promoting phospholipid synthesis and VLDL formation — the mechanism by which the liver packages and ships triglycerides out of hepatocytes.
Enhances cellular glucose uptake and insulin signaling. Research shows myo-inositol supplementation reduces visceral adiposity and improves metabolic parameters in PCOS and metabolic syndrome. Supports healthy fat distribution and mood regulation as a secondary benefit.
Required for VLDL synthesis and fat export from the liver. Acts as a methyl donor and precursor to acetylcholine. Maintains phospholipid membrane integrity and neurological function. Deficiency is linked to hepatic fat accumulation and impaired cognitive function.
The science behind each compound.
Lipotropic ingredients have decades of clinical research supporting their metabolic benefits.
Statements above reflect general published research and standard biochemistry. Specific quantitative claims for injectable B12 + MIC formulations have not been established in randomized controlled trials. Compounded formulations are not FDA-approved. Individual results vary. Prescription required.
Prescribed For
*Research support indicates published clinical evidence. Compounded MIC is not FDA-approved.
Complete B12 + MIC bundle. One flat price.
Physician consultation & protocol design
Our providers assess your energy needs, metabolic goals, current health status, and design a personalized injection schedule — weekly, twice-weekly, or custom dosing.
Compounded B12 + MIC vials
Clinical-grade compounded B12 + MIC solution (methylcobalamin plus methionine, inositol, and choline), sterile-packaged, with proper concentration and stability testing per compounding pharmacy standards.
Syringes & injection supplies
Sterile syringes, alcohol prep pads, and sharps disposal container — everything needed for safe at-home subcutaneous or IM injection.
Injection protocol & guidance
Detailed instructions on proper injection technique, site rotation, storage requirements, and troubleshooting. Video resources available.
Ongoing provider support
Check-ins, dose adjustments if needed, integration guidance with other therapies (GLP-1, fitness protocols), and dedicated support throughout your treatment.
What to expect over time
Protocol Established
Injection protocol initiated. Early energy improvements may be noticed. Liver enzymes begin responding to increased nutritional support.
Metabolic Support Active
Liver enzyme support evident. Enhanced fat mobilization becomes measurable alongside consistent diet and exercise. Energy and recovery improve noticeably.
Body Composition Changes
Measurable improvements in body composition, particularly when combined with GLP-1 therapy or consistent training. Visceral fat reduction most pronounced in this window.
Sustained Protocol
Best used as a long-term metabolic support therapy alongside other interventions. Continued liver health, steady fat mobilization, and metabolic optimization.
Safety & Considerations
MIC injections are generally very well tolerated. Your Obsidian Genetics provider will review your full health history before prescribing.
⚠ Important Safety Considerations
Not recommended if you have trimethylaminuria (TMAU) — a rare genetic condition affecting choline metabolism. High-dose choline can cause a fishy body odor. Monitor liver enzymes if combining with other hepatotoxic compounds or if you have pre-existing liver disease. MIC is not contraindicated in standard use, but baseline liver function testing is recommended before starting, especially with sustained long-term use.
Frequently asked question
What's the difference between MIC and B12 injections?
B12 (cyanocobalamin) supports energy production and neurological function. MIC injections target fat metabolism and liver health specifically. While some providers offer “MIC-B12” (MIC combined with B12), they serve different physiological roles. MIC is prescribed for metabolic optimization; B12 for energy and neurological support. Many protocols use both together for complementary effects.
How often do I inject MIC?
Frequency is determined by your provider and metabolic goals. Common schedules are weekly (1x/week) or twice-weekly (2x/week). Some patients use twice-weekly during active weight loss or metabolic optimization phases, then shift to weekly maintenance. Your Obsidian Genetics provider will establish the schedule that best fits your protocol.
Can I take MIC while on semaglutide or tirzepatide?
Yes. In fact, MIC and GLP-1 drugs are synergistic. While semaglutide reduces appetite and calorie intake, MIC supports hepatic fat export and metabolic efficiency. Many patients use MIC alongside GLP-1 therapy for enhanced body composition results. Your provider will coordinate dosing schedules and monitor response.
Will MIC help me lose weight on its own? +
MIC is not a standalone weight loss drug. It works best as part of a comprehensive metabolic protocol that includes diet, exercise, and often other therapies like GLP-1 drugs. MIC’s strength is supporting the metabolic machinery that makes weight loss sustainable — fat export, liver health, and insulin sensitivity. Think of it as optimizing how your body processes and mobilizes stored fat, not as appetite suppression.
Is this the same as "lipo shots" I've heard about?
“Lipo shots” is an older colloquial term for lipotropic injections — which is exactly what MIC is. MIC (methionine, inositol, choline) is the clinical formulation of the lipotropic compound. Obsidian Genetics uses pharmaceutical-grade, physician-supervised compounded MIC — not generic wellness clinic injections. We ensure proper dosing, sterility, and integration with your full treatment plan.
How is the MIC injection administered?
MIC is administered as a subcutaneous injection (under the skin) or intramuscular injection (into muscle), depending on your provider’s recommendation. Most patients self-inject at home after a brief training session. Common injection sites are the abdomen, thigh, or upper arm. Your kit includes everything you need — syringes, prep pads, and sharps disposal — plus video guidance.
How should I store MIC?
Store vials in the refrigerator between 36°F–46°F (2°C–8°C). Do not freeze. MIC solutions are temperature-sensitive and can degrade if frozen or left at room temperature for extended periods. Keep out of direct light. When traveling, use a medical-grade cooler or insulated bag for transit periods longer than a few hours.
Important: This product is a compounded B12 + MIC injection bundle — a preparation containing methylcobalamin (B12), methionine, inositol, and choline made by a licensed compounding pharmacy. B12 + MIC injections are not FDA-approved drug products. Their safety and effectiveness have not been independently verified by the FDA. This is not an FDA-approved pharmaceutical and is prescribed by a licensed healthcare provider for individual patient use. A licensed Obsidian Genetics physician will evaluate your health history and determine whether B12 + MIC injections are appropriate for you. Prescription required. Individual results vary. Research statistics cited on this page reflect published clinical studies on B12 and lipotropic compounds — results with compounded B12 + MIC injections have not been independently verified in double-blind clinical trials. Always disclose all medications and health conditions to your provider. Do not use if you have trimethylaminuria (TMAU) or uncontrolled liver disease. Monitor liver enzymes if combining with other hepatic compounds or with sustained long-term use.