Energy back. Body rebuilt. Mind sharp.
Vitality, reclaimed.
Three compounds working on your metabolism, your recovery, and your cellular engine. No GLP-1. No appetite suppression. Pure performance and energy restoration.
Not every protocol is about weight loss. Sometimes the goal is getting your energy back, recovering the way you used to, and feeling like your body is actually working for you again. B12 supports energy production at the cellular level and restores nerve and blood cell function. Sermorelin restores the growth hormone signal that drives recovery and sleep quality. NAD⁺ rebuilds the mitochondrial engine that makes sustained energy possible. This is the stack for people who want to feel better — and perform better — without changing their appetite.
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Three signals. One coordinated result.
Each compound in this stack targets a distinct physiological pathway. Together, they create a layered system that addresses metabolism, recovery, and energy — simultaneously and without conflict.
Cellular Energy Foundation
Injectable B12 (methylcobalamin) bypasses the gut for full bioavailability, supporting red blood cell production, nerve function, and cellular energy metabolism. This creates a stable baseline of energy production and prevents the fatigue that comes from suboptimal B12 status — common in adults over 40.
GH-Axis Recovery
Sermorelin signals the pituitary to restore natural growth hormone pulses. This drives muscle recovery, improves deep sleep quality, and accelerates tissue repair — the biological foundation of feeling strong and recovered every morning.
Mitochondrial Fuel
NAD⁺ directly fuels the cellular energy production cycle. It rebuilds mitochondrial function and sustains the ATP production that makes all-day energy possible — the difference between dragging and actually performing.
What's in this stack and why.
Every component is chosen for a specific role. There is no redundancy here — each compound addresses something the others cannot.
B12 (Methylcobalamin)
Injectable B12 (methylcobalamin) is essential for red blood cell formation, nerve function, and cellular energy metabolism. Delivered via subcutaneous injection, it bypasses the digestive system for full bioavailability — critical for adults over 40, where absorption declines and low B12 is a common driver of fatigue.
In this stack, B12 provides the cellular energy foundation. It restores the baseline energy production that gets depleted with age, stress, and metabolic decline — without stimulants or appetite changes.
Sermorelin
Sermorelin is a bioidentical analog of growth hormone-releasing hormone (GHRH). It works upstream — signaling your pituitary gland to release your own natural growth hormone in the same pulsatile rhythm your body was designed for. This is fundamental: you're not adding external hormone; you're restoring your body's own signal.
The result is improved muscle recovery, deeper sleep, better tissue repair, and the kind of physical resilience that lets you train hard and actually recover from it. This is what allows you to maintain performance when your energy systems are being supported.
NAD⁺
NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme central to how your cells produce usable energy. Levels decline with age and drop further under stress and sustained high output. When NAD⁺ is depleted, you feel it immediately — fatigue, brain fog, reduced physical capacity.
By restoring NAD⁺ levels, this component directly addresses the energy substrate that sustains performance. You get clearer focus, maintained physical output throughout the day, and the cellular capacity to recover and perform consistently.
Without this stack vs. with it.
This is the difference between managing chronic fatigue and actually performing. Every element of this stack was chosen to address a specific energy system. Together, they create the foundation for sustained vitality.
Declining Baseline
Energy + Recovery Restored
The Bottom Line
This stack is designed for people whose foundational energy systems have declined but whose goals are not about weight loss. B12 restores your cellular energy baseline without stimulants. Sermorelin restores the recovery signal. NAD⁺ fuels the cellular machinery that makes it all work. The result is that you feel like yourself again — with the energy and recovery capacity you remember having.
A protocol that builds on itself.
Results from this stack are progressive and compound over time. The first few weeks bring initial energy shifts. By month two, the difference becomes undeniable.
Initial Energy Lift
Recovery Noticeably Faster
Sustained Energy Baseline Elevated
New Performance Ceiling
Built for people who want their energy back.
This is for high performers, athletes, and people who have watched their energy gradually decline — and want it restored. No weight loss goal required. Just performance, recovery, and the energy to live the way you used to.
Stack At a Glance
Common Questions
Is this stack for weight loss?
No. This stack is designed to restore energy, improve recovery, and support your metabolic health — without appetite suppression or weight loss focus. B12 supports cellular energy production, but the primary benefit is sustainable energy — not weight loss or appetite changes. If weight loss is your goal, consider the GLP-1-based stacks.
Can women use this stack?
Yes. All three compounds are appropriate for both men and women. B12, Sermorelin, and NAD⁺ have well-established safety profiles across genders. Your prescribing physician will review your health history and confirm this protocol is appropriate for you.
Do I need labs before starting?
No prerequisite labs are required for this stack. Your prescribing physician will review your intake health history. Labs may be recommended based on your individual situation, but they are not required to begin this protocol.
How much commitment is the injection schedule?
B12 is once weekly, Sermorelin is nightly pre-bed (a small injection under a minute), and NAD⁺ is daily. Your care team will walk you through injection technique during your consultation. The nightly injections become routine quickly and are nearly imperceptible.
Can I combine this with other protocols?
Stacks should not be combined with other stacks or treatments containing the same compounds. If you’re already on B12, Sermorelin, or NAD⁺ through another source, speak with your care team before adding this protocol. Your physician will assess for any overlap.
This stack, prescribed
for you specifically.
Every Obsidian protocol is reviewed and prescribed by a board-certified physician based on your health history, goals, and how your body is responding. This is not a subscription box. It is a medical protocol.
Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. All treatments described are prescribed by licensed physicians based on individual patient health history and clinical evaluation. Results vary. These statements have not been evaluated by the Food and Drug Administration. Obsidian Genetics treatments are not intended to diagnose, treat, cure, or prevent any disease. Consult your prescribing physician before starting, stopping, or modifying any medical protocol.