● Weight Loss (Sustainable)

Steady progress. Sustained energy. No crash. Long-game weight loss.

A lower-dose approach to GLP-1 combined with recovery support. Built for people who want sustainable results without the intensity of full suppression.

Full-dose GLP-1 isn't for everyone. Some people want the metabolic benefit without aggressive appetite suppression — the kind of sustainable shift you can maintain long-term. Micro-dose GLP delivers mild metabolic modulation: appetite awareness without elimination, weight movement without the fatigue wall. Combined with Sermorelin's recovery signal, this is the stack for people playing the long game.

Micro Dose GLP-1 + Sermorelin Stack
Includes both compounds, ongoing provider care, syringes & supplies, and platform access.
Starting at
$279.00
Billed monthly
Includes Ongoing Provider Care & Support
Syringes & Alcohol Pads · Platform Access & Educational Content
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100% Online
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Board-Certified
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Fast Shipping
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You've tried full-dose GLP-1 and found the side effects too intense
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You want sustainable, steady progress — not aggressive short-term suppression
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You're looking for a protocol you can maintain for months, not weeks
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You want metabolic support without feeling like you're medicating your hunger into nothing
01
Micro Dose GLP-1
Gentle Metabolic Modulation
+
02
Sermorelin
GH Recovery Signal
Signal Model

Two signals. One sustainable rhythm.

Each compound works at a different level to create metabolic support without overwhelming your system. Together, they create a pace you can maintain.

Signal 01
⬇

Mild Metabolic Modulation

Micro GLP

Micro-dose GLP-1 provides gentle appetite awareness and metabolic shift without full suppression. You still feel hunger signals, but they're quieter. Weight moves steadily without the fatigue or intensity of full-dose approaches.

Signal 02
↑

GH-Axis Recovery

Sermorelin

Sermorelin signals the pituitary to maintain natural growth hormone pulses, protecting lean mass and supporting deep, restorative sleep — the foundation of sustainable progress.

Each Compound

What's in this stack and why.

Every component is chosen for sustainability. This is not about speed — it's about the pace you can maintain for life.

Component 01

Micro Dose GLP-1

Gentle Metabolic Support

A lower-dose GLP-1 protocol delivers metabolic benefits without aggressive appetite suppression. You maintain awareness of hunger and fullness cues — the body's natural feedback system — while benefiting from improved metabolic efficiency and mild appetite reduction.

This approach is designed for people who want steady, sustainable weight loss without the intensity of full-dose GLP-1. Side effects are minimal, and the pace is maintainable long-term.

Dosing Frequency
Micro Dose Weekly
Timing
Consistent Day, AM or PM
Delivery
Subcutaneous Injection
Component 02

Sermorelin

Recovery + Sleep Support

Sermorelin is a bioidentical analog of growth hormone-releasing hormone (GHRH). It signals your pituitary gland to release natural growth hormone in the same pulsatile rhythm your body was designed for.

During any caloric reduction, sleep quality and recovery can suffer. Sermorelin protects lean tissue, improves deep sleep architecture, and ensures you feel recovered — not depleted — as the weeks progress.

Dosing Frequency
Nightly
Timing
Pre-Bed, Fasted State
Delivery
Subcutaneous Injection
How This Stack Runs

Gentle approach vs. aggressive suppression — what you gain and what you don't.

This stack is built for the long game. You get steady progress, manageable side effects, and a protocol you can sustain without feeling like you're white-knuckling your way through.

Comparison

Full Dose GLP-1

✓
Intense appetite suppression — weight loss is rapid
✗
Intense side effects — nausea, fatigue, food aversions
✗
Unsustainable long-term — most people can't maintain it
✗
Energy crashes — especially during workouts
✗
Muscle risk — without recovery support
With This Stack

Micro GLP + Sermorelin

✓
Weight loss at a sustainable pace — gentler, more manageable
✓
Fewer side effects — you feel more like yourself throughout the protocol
✓
Sustainable long term — a pace you can maintain indefinitely
✓
Muscle preserved — Sermorelin keeps your lean mass protected
✓
Sleep improved — deep, restorative recovery every night

The Bottom Line

Full-dose GLP-1 is fast but unsustainable for most people. This stack is slower but sustainable. You still get consistent fat loss, but you maintain energy, sleep quality, and the ability to train. It's the difference between a sprint and a marathon.

What to Expect

Steady, consistent, sustainable progress.

Results from this stack compound over months, not weeks. The pace is slower than full-dose GLP-1, but the sustainability is unmatched.

Weeks 1–4

Gentle Adjustment

→ Body adjusts to mild appetite shift
→ Minimal side effects — you feel normal
→ Sleep quality begins improving
→ Energy remains stable and consistent
Weeks 5–10

Steady Progress

→ Consistent weekly weight movement
→ Mild metabolic shift taking hold
→ Recovery between workouts improving
→ Sleep architecture visibly better
Weeks 11–20

Long-Term Recomposition

→ Body composition shifting steadily
→ Lean mass protected and stable
→ Sustained energy throughout the day
→ Training performance maintained
→ Momentum clear and compounding
Month 6+

Sustainable Maintenance

→ New body composition baseline locked in
→ Dose optimization with your physician
→ Continue Sermorelin for sustained quality
→ Protocol review and long-term planning
Who This Stack Is For

Built for the long game.

This is the stack for someone who wants metabolic support without the intensity of full-dose GLP-1. You value consistency over speed, sustainability over a quick fix, and you're willing to play the long game for results you can maintain forever.

→
You've tried full-dose GLP-1 and found the side effects intolerable
→
You want sustainable progress you can maintain indefinitely
→
Energy and sleep quality matter — you don't want to sacrifice them
→
You value a stable approach over aggressive short-term results
→
You're looking for a protocol that fits your life, not one that disrupts it

Stack At a Glance

Primary Goal
Sustainable Fat Loss
Category
Weight Loss (Sustainable)
Gender
All
Labs Required
No
Compounds
2
Injection Days
Micro GLP Weekly + Nightly
Supervised By
Board-Certified Physician
2
Compounds
Focused approach for sustainable fat loss
0
Labs Required
Get started without prerequisite bloodwork
∞
Sustainability
A protocol you can maintain indefinitely
80%
Side Effect Reduction
Minimal to no nausea, energy stays steady
Common Questions

Common Questions

Micro-dose GLP-1 typically delivers 1-1.5 pounds of weight loss per week on average, compared to 2-3+ pounds per week with full-dose. This is steady, consistent progress that most people can maintain indefinitely without side effects. Your physician will tailor the dose based on your response and goals.

Sermorelin protects your lean tissue and ensures the weight you lose is fat, not muscle. Even at lower GLP-1 doses, your body needs support to preserve muscle during a caloric deficit. Sermorelin also improves sleep quality, which is critical for long-term sustainability and recovery.

Yes. If you start with micro-dose and want to increase intensity later, you can work with your physician to adjust the protocol. Many people start with micro-dose to test tolerance, then increase if desired. This stack is flexible and tailored to your needs.

Yes. Both micro-dose GLP-1 and Sermorelin are appropriate for men and women. These compounds have well-established safety profiles across genders. Your prescribing physician will review your health history and tailor the approach for you.

No prerequisite labs are required. Your prescribing physician will review your intake health history. Labs may be recommended based on your individual situation, but they are not required to begin this protocol.

Get Started

This stack, prescribed
for you specifically.

Every Obsidian protocol is reviewed and prescribed by a board-certified physician based on your health history, goals, and how your body is responding. This is not a subscription box. It is a medical protocol.

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Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. All treatments described are prescribed by licensed physicians based on individual patient health history and clinical evaluation. Results vary. These statements have not been evaluated by the Food and Drug Administration. Obsidian Genetics treatments are not intended to diagnose, treat, cure, or prevent any disease. Consult your prescribing physician before starting, stopping, or modifying any medical protocol.