Sleep restored. Energy rebuilt. Body reset.
The foundation stack.
Two compounds. The most essential recovery and energy protocol. Start here if everything else has stopped working the way it should.
Sometimes the problem isn't one big thing — it's that your foundational systems have quietly degraded. GH production declining year over year. NAD⁺ levels dropping with age and stress. The result is a body that doesn't recover fully, doesn't sleep deeply, and doesn't have the cellular energy to perform the way it used to. This two-compound stack addresses both simultaneously. Sermorelin restores the natural GH signal that drives overnight recovery and tissue repair. NAD⁺ rebuilds the cellular energy system from the inside out. Simple, clean, and foundational.
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Two signals. One simple foundation.
This stack addresses the two foundational systems that decline with age and stress. Rebuild both, and everything else becomes possible again.
Cellular Energy Restoration
NAD⁺ is the coenzyme responsible for mitochondrial energy production. Levels decline with age and stress. By restoring NAD⁺, you're rebuilding the cellular engine that powers everything — from sleep quality to your ability to recover from exercise to your baseline energy throughout the day.
GH-Axis Recovery
Sermorelin restores pituitary GH pulses — the primary driver of overnight repair and sleep quality. This is what allows your body to actually recover while you rest, repair tissue, and wake up genuinely refreshed instead of just rested.
What's in this stack and why.
This is the simplest stack: two foundational compounds that address the core systems that decline with age. No redundancy. No excess. Just what matters.
NAD⁺
NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme essential to mitochondrial function. Your cells use NAD⁺ to convert nutrients into usable energy (ATP). Levels naturally decline with age, stress, and reduced sleep quality. When NAD⁺ is depleted, you feel it: fatigue, poor recovery, brain fog, reduced physical capacity.
By restoring NAD⁺, you're directly addressing the energy substrate that powers your entire system. The result is more sustained energy throughout the day, better recovery capacity, and improved overall function.
Sermorelin
Sermorelin is a bioidentical analog of growth hormone-releasing hormone (GHRH). It signals your pituitary gland to release your own natural growth hormone in the same pulsatile pattern your body was designed for. Growth hormone is the primary driver of overnight tissue repair, recovery, and sleep quality.
As you age, GH production naturally declines — which is why recovery gets slower and sleep quality suffers. Sermorelin restores this signal, allowing your body to actually recover while you sleep and wake up genuinely recovered instead of just rested.
Without support vs. with this stack.
This is the difference between a declining baseline and restoring it. Two simple compounds working on the two systems that matter most: energy and recovery.
Declining Baseline
Foundation Restored
The Bottom Line
This is the foundation. NAD⁺ rebuilds your cellular energy system. Sermorelin restores the recovery signal that drives overnight repair. Together, they address the core systems that decline with age and stress. This is where to start if everything else has stopped working the way it should.
A protocol that restores your foundation.
Results from this stack are progressive. Sleep improves first. Energy follows. By month four, you're noticeably stronger and more recovered than you've been in years.
Sleep Quality Shifts
Energy More Consistent
Recovery Noticeably Faster
New Energy + Recovery Baseline
Built for people whose foundations have degraded.
This is the simplest stack: for people whose energy and recovery have declined gradually, who want to start with a clean foundation, and who don't need complex multi-compound protocols yet.
Stack At a Glance
Common Questions
Is this stack for weight loss?
No. This stack focuses on restoring energy and recovery. While improved NAD⁺ and sleep quality can support metabolic health, the primary goal is rebuilding your foundational systems, not weight loss. If weight loss is your goal, consider GLP-1-based stacks.
Can both men and women use this?
Yes. Both NAD⁺ and Sermorelin are appropriate for men and women. Both compounds have well-established safety profiles across genders. Your prescribing physician will review your health history and confirm this protocol is appropriate for you.
Do I need labs before starting?
No prerequisite labs are required for this stack. Your prescribing physician will review your intake health history. Labs may be recommended based on your individual situation, but they are not required to begin this protocol.
How simple is the injection schedule?
Very simple. NAD⁺ is daily, morning or IV, and Sermorelin is nightly pre-bed as a small injection under a minute. This is the simplest schedule of any stack. Your care team will walk you through injection technique during your consultation.
Can I add more compounds to this later?
Yes. This is positioned as a foundation. Many people start here and add compounds like B12+MIC or GLP-1 later as their needs evolve. Your physician can assess what makes sense for you as your situation changes.
This stack, prescribed
for you specifically.
Every Obsidian protocol is reviewed and prescribed by a board-certified physician based on your health history, goals, and how your body is responding. This is not a subscription box. It is a medical protocol.
Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. All treatments described are prescribed by licensed physicians based on individual patient health history and clinical evaluation. Results vary. These statements have not been evaluated by the Food and Drug Administration. Obsidian Genetics treatments are not intended to diagnose, treat, cure, or prevent any disease. Consult your prescribing physician before starting, stopping, or modifying any medical protocol.