● Exercise + Performance

Train harder. Recover faster.
Perform at your peak.
The performance stack.

Three compounds that support blood flow, growth hormone recovery, and metabolic energy — designed for men who demand more from their bodies.

Performance isn't just about what happens during a workout. It's about the blood flow that delivers oxygen and nutrients when you need them most, the recovery signals that rebuild tissue while you sleep, and the metabolic support that keeps your energy levels where they need to be. Tadalafil taken daily supports vascular function and circulation. Sermorelin restores the natural GH pulse that drives overnight muscle repair and sleep quality. Weekly B12 injection maintains the neurological and metabolic foundation that sustained performance depends on.

Sermorelin + Tadalafil + B12 Stack
Includes all 3 compounds, ongoing provider care, syringes & supplies, and platform access.
Includes Ongoing Provider Care & Support
Syringes & Alcohol Pads · Platform Access & Educational Content
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Board-Certified
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You train consistently and want every session to count — and recover from
Blood flow and vascular performance are part of your optimization plan
You wake up from training feeling flat — recovery isn't keeping up with your output
You want a performance protocol that works while you train and while you sleep
01
Sermorelin
GH Recovery Signal
+
02
Tadalafil Daily
Vascular Performance
+
03
B12 Weekly
Metabolic + Neurological
Signal Model

Three signals. One coordinated result.

Each compound in this stack targets a distinct physiological pathway. Together, they create a layered system that optimizes blood flow, recovery, and metabolic support — all working in sync whether you're in the gym or sleeping.

Signal 01

Overnight GH Restoration

Sermorelin

Sermorelin signals the pituitary to restore natural growth hormone pulses — the same rhythm that drives muscle repair and tissue recovery during sleep. Enhanced overnight recovery means stronger performance the next day.

Signal 02

Vascular Performance

Tadalafil

Daily tadalafil support for blood flow and circulation, delivering more oxygen and nutrients to working muscle during training and enhancing the pump when it matters most for performance.

Signal 03
🧠

Metabolic Foundation

B12

Weekly B12 injection maintains the neurological and red blood cell function that sustained performance depends on — supporting energy production and cognitive sharpness across training cycles.

Each Compound

What's in this stack and why.

Every component is chosen for a specific role in performance optimization. There is no redundancy here — each compound addresses something the others cannot.

Component 01

Sermorelin

Recovery Signal

Sermorelin is a bioidentical analog of growth hormone-releasing hormone (GHRH). It signals your pituitary gland to release your own natural growth hormone in pulsatile rhythm — restoring the recovery signal that intensive training depletes.

In a performance context, this matters because training breaks muscle tissue down. Sermorelin accelerates the overnight repair phase, enhances sleep quality, and ensures recovery keeps pace with training volume. The result is sustainable progression without degradation.

Dosing Frequency
Nightly
Timing
Pre-Bed, Fasted State
Delivery
Subcutaneous Injection
Component 02

Tadalafil Daily

Vascular Support

Tadalafil is a phosphodiesterase-5 inhibitor that supports vascular function and blood flow through smooth muscle relaxation. Daily dosing maintains consistent support for circulation, oxygen delivery, and nutrient transport to working tissue.

In a performance context, enhanced blood flow means better oxygen availability during training, faster nutrient delivery to muscles, and improved endothelial function. This directly amplifies the effect of each training session and supports recovery pathways.

Dosing Frequency
Daily
Timing
Consistent Time, Daily
Delivery
Oral
Component 03

B12 Weekly

Metabolic + Neurological Support

Vitamin B12 (cobalamin) is essential for red blood cell formation, neurological function, and energy metabolism. Weekly injection ensures sustained levels of this critical cofactor, supporting the metabolic machinery that powers performance.

In a performance context, B12 maintains the neurological and metabolic foundation that training relies on. It supports energy production, cognitive focus, and recovery signaling — preventing the metabolic degradation that can occur with high training volume.

Dosing Frequency
1× Weekly
Timing
Consistent Day, AM or PM
Delivery
Intramuscular Injection
How This Stack Runs

Training Without Support vs. With This Stack

Training hard demands recovery. This stack is designed to match your output with the physiological support your body needs to adapt, rebuild, and perform at a higher ceiling consistently.

Without Support

Training Alone

Incomplete recovery — GH signal fades with age
Limited blood flow — oxygen and nutrient delivery plateaus
Metabolic gaps — energy and neurological support decline
Performance plateauing — recovery can't keep pace with training

The Bottom Line

This stack is designed for the athlete or trainee who has committed to serious performance and wants every recovery window optimized. Sermorelin restores the GH pulse. Tadalafil maximizes blood flow. B12 maintains the metabolic foundation. Together, they ensure your body can adapt and progress at the pace your training demands.

What to Expect

A protocol that compounds recovery.

Results from this stack progress across distinct phases. The first month establishes the foundation. Weeks 4-8 show acceleration in recovery speed. By week 9+, training performance visibly improves as the stack effects compound.

Weeks 1–3

Foundation Building

→ Vascular and energy foundation establishing
→ Sleep quality begins improving
→ Recovery window shortening slightly
→ B12 levels normalizing
Weeks 4–8

Recovery Acceleration

→ Recovery speed noticeably increases
→ Sleep architecture improving — deeper rest
→ Training session quality improving
→ Energy consistency rising
Weeks 9–16

Performance Peak

→ Training performance visibly improved
→ Stamina and work capacity elevated
→ Recovery between sessions accelerated
→ Strength gains compounding
→ Full stack synergy operating
Month 5+

New Baseline Locked

→ Performance ceiling established at new level
→ Sustainability at higher training volume
→ Continue all three compounds for maintenance
→ Protocol reviewed by physician
Who This Stack Is For

Built for men serious about performance.

This is not a beginner protocol. This is the stack for someone who trains consistently, who understands that recovery is where adaptation happens, and who wants medically supervised support to match their training ambition.

You train consistently and want every session to count and recover from
Blood flow and vascular performance are part of your optimization plan
You wake up from training feeling flat — recovery isn't keeping up with output
You want a performance protocol that works while you train and while you sleep

Stack At a Glance

Primary Goal
Performance + Recovery
Category
Exercise + Performance
Gender
Men
Labs Required
No
Compounds
3
Protocol Schedule
Daily + Weekly
Supervised By
Board-Certified Physician
3
Compounds
Each targeting a distinct performance pathway
0
Labs Required
Get started immediately with physician oversight
Daily + Weekly
Protocol Schedule
Tadalafil daily + Nightly Sermorelin + Weekly B12
Men's
Protocol
Optimized for male physiology and performance goals
Common Questions

Common Questions

Each compound addresses a distinct aspect of performance. Sermorelin restores the overnight recovery signal, growth hormone, that training disrupts. Tadalafil optimizes blood flow and oxygen delivery during and after training. B12 maintains the neurological and metabolic foundation that sustained performance depends on. Together, they create a unified protocol that addresses recovery, vascular function, and metabolic support simultaneously.

This protocol has been specifically optimized for men’s physiology and performance goals. Sermorelin, Tadalafil, and B12 are all used across genders, but the dosing, timing, and outcomes of this particular stack are designed for male athletes and trainees. If you are a woman interested in a performance protocol, speak with your Obsidian physician about stacks tailored to your physiology.

No prerequisite labs are required for this stack. Your prescribing physician will review your intake health history to ensure the protocol is appropriate for you. Labs may be recommended based on your specific situation, but they are not required to begin.

Sermorelin is a small nightly subcutaneous injection, pre-bed, and takes under a minute. B12 is a weekly intramuscular injection. Tadalafil is oral, taken daily. Your care team walks you through proper injection technique during your onboarding consultation, and you’ll have full support throughout the protocol.

Stacks should not be combined with other stacks or treatments that contain the same compounds. If you are already using any of these compounds through another protocol, speak with your care team. Your physician will assess for any overlap and adjust your protocol accordingly.

Get Started

Performance support,
prescribed for you.

Every Obsidian protocol is reviewed and prescribed by a board-certified physician based on your training history, goals, and how your body is responding. This is not a supplement. It is a medical protocol.

Medical Disclaimer: This page is for informational purposes only and does not constitute medical advice. All treatments described are prescribed by licensed physicians based on individual patient health history and clinical evaluation. Results vary. These statements have not been evaluated by the Food and Drug Administration. Obsidian Genetics treatments are not intended to diagnose, treat, cure, or prevent any disease. Consult your prescribing physician before starting, stopping, or modifying any medical protocol.